What is the natural history of genital herpes? What is the natural history of genital herpes?

What is the natural history of genital herpes?

Primary genital herpes refers to the first infection with the herpes simplex virus, with an incubation period of 3 to 9 days, usually about 5 days. The symptoms of primary genital herpes vary greatly and are not limited to a certain pattern, ranging from no clinical manifestations to severe genital ulcers, such as erosive balanitis or vulvovaginitis or proctitis, and sometimes need to be distinguished from genital ulcers caused by other sexually transmitted diseases.

The affected part first has a burning and itching sensation, and erythema appears. Soon, clusters of small blisters occur on the base of the erythema. The small blisters can break or turn into small pustules within 2 to 3 days. After the blisters break, erosion or ulceration is formed. The blister process usually lasts about 10 days, and the patient feels pain (burning pain or tingling). Finally, the scab heals. The whole course of the disease is 10 to 20 days. Male genital herpes is prone to occur in the foreskin, glans, coronal sulcus, penis, scrotum, urethral orifice, etc. Women are prone to the labia, mons pubis, clitoris, vagina, and some patients may also occur in the cervix. Male homosexuals can also invade the anus and rectum. In severe cases, proctitis occurs, and the anal canal and rectal mucosa are widely eroded. The incidence of systemic symptoms of primary genital herpes is high, and there may be fever, headache, general discomfort and muscle aches, etc. The course of the disease is long and the rash is severe.